Threshold expression

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Threshold Expression

Threshold expression (pronunciation: /ˈθrɛʃˌhoʊld ɪkˈsprɛʃən/) is a term used in medicine and genetics to describe the minimum level of a gene or protein that must be present in a cell for a certain biological process or reaction to occur.

Etymology

The term "threshold" originates from the Old English words "þrescold" (threshold) and "þrescan" (to thresh), which referred to the separation of grain from its husk. In a metaphorical sense, it was used to denote the point or level at which something begins or changes. The term "expression" in this context is derived from the Latin "expressio", meaning "the action of making something explicit".

Related Terms

  • Gene Expression: The process by which information from a gene is used to create a functional product, usually a protein.
  • Protein Expression: The process by which proteins are synthesized, modified, and regulated in living organisms.
  • Threshold Trait: A trait in which a certain value (the threshold) must be exceeded before an effect is observed.
  • Threshold Model: A statistical model used in genetics to analyze traits that are either present or absent, based on a certain threshold.
  • Quantitative Trait Loci (QTL): Locations on the genome that are associated with the variation of a quantitative trait.

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