Sisomicin

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Sisomicin

Sisomicin (pronounced: si-so-mi-cin) is an aminoglycoside antibiotic that is used to treat various types of bacterial infections. It was first isolated in 1973 from the fermentation broth of Micromonospora inyoensis, a species of bacteria found in soil.

Etymology

The term "Sisomicin" is derived from the name of the bacterium from which it was first isolated, Micromonospora inyoensis. The "-micin" suffix is common in the names of aminoglycoside antibiotics, indicating their origin from various species of bacteria.

Usage

Sisomicin is used to treat a wide range of bacterial infections, particularly those caused by Gram-negative bacteria. It works by inhibiting protein synthesis in the bacterial cell, leading to cell death. It is often used in combination with other antibiotics to treat severe or resistant infections.

Related Terms

  • Aminoglycoside: A class of antibiotics that includes sisomicin. They are typically used to treat serious infections caused by Gram-negative bacteria.
  • Antibiotic: A type of medication used to treat bacterial infections. Antibiotics work by killing bacteria or inhibiting their growth.
  • Gram-negative bacteria: A type of bacteria that does not retain the crystal violet stain used in the Gram staining method of bacterial identification. They are often more resistant to antibiotics than Gram-positive bacteria.
  • Protein synthesis: The process by which cells make proteins. Inhibition of protein synthesis is one of the ways that antibiotics like sisomicin work to kill bacteria.

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