Salmonella Typhi

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Salmonella Typhi

Salmonella Typhi (pronounced: sal-muh-nel-uh tahy-fahy) is a Gram-negative bacteria that causes typhoid fever, a potentially life-threatening illness. The term "Salmonella" is derived from the name of the American scientist Daniel Elmer Salmon, who first identified the bacteria, while "Typhi" is derived from the Greek word "typhos", meaning smoke or cloud, which metaphorically refers to the state of confusion often associated with the disease.

Description

Salmonella Typhi is a flagellated bacterium, meaning it has whip-like appendages that allow it to move. It is part of the Enterobacteriaceae family, which also includes other disease-causing bacteria such as Escherichia coli and Klebsiella pneumoniae. Salmonella Typhi is unique among other Salmonella species in its ability to cause systemic infections and its human-restricted host range.

Transmission

Salmonella Typhi is transmitted through the fecal-oral route, meaning it is spread through contaminated food or water. It can also be spread through close contact with an infected person. Once ingested, the bacteria invade the intestinal epithelium and can spread to other parts of the body through the bloodstream.

Symptoms and Treatment

Symptoms of infection with Salmonella Typhi include high fever, headache, abdominal pain, and constipation or diarrhea. Treatment typically involves antibiotics, although resistance to multiple drugs is increasingly common. Vaccines are available and recommended for those traveling to areas where typhoid fever is common.

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