Origin of replication
Origin of Replication
Origin of Replication (pronunciation: /ɔːrɪdʒɪn ɒv ˌrɛplɪˈkeɪʃən/) is a specific sequence in a genome where DNA replication begins.
Etymology
The term "Origin of Replication" is derived from the Latin words 'origo' meaning 'beginning' and 'replicare' meaning 'to repeat'. It refers to the starting point where the process of DNA replication occurs.
Definition
The Origin of Replication, often abbreviated as ori, is a particular sequence in a genome at which replication is initiated. This can either involve the replication of DNA in living organisms such as prokaryotes and eukaryotes, or that of DNA or RNA in viruses, viroids and plasmids.
Function
The main function of the Origin of Replication is to provide a starting point for DNA replication. It is where the two DNA strands are separated and opened up to allow the enzymes involved in DNA replication, such as DNA polymerase, to access the DNA and begin synthesizing a new strand.
Related Terms
- DNA replication: The process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules.
- Genome: The complete set of genes or genetic material present in a cell or organism.
- DNA polymerase: An enzyme that synthesizes DNA molecules from deoxyribonucleotides, the building blocks of DNA.
See Also
External links
- Medical encyclopedia article on Origin of replication
- Wikipedia's article - Origin of replication
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