Indeterminate cell histiocytosis
Indeterminate Cell Histiocytosis
Indeterminate Cell Histiocytosis (pronunciation: in-de-ter-mi-nate cell his-ti-o-cy-to-sis) is a rare form of histiocytosis, a group of diseases characterized by an abnormal increase in the number of histiocytes, a type of white blood cell.
Etymology
The term "Indeterminate Cell Histiocytosis" is derived from the Latin word 'indeterminatus', meaning 'undefined', and the Greek words 'histio', meaning 'tissue', and 'kytos', meaning 'cell', and 'osis', meaning 'condition'. This term is used to describe a condition where the cells involved are not clearly defined or classified.
Definition
Indeterminate Cell Histiocytosis is a rare disorder characterized by the accumulation of histiocytes, which are part of the immune system. These cells are neither Langerhans cells nor monocytes, but have characteristics of both, hence the term 'indeterminate'.
Symptoms
The symptoms of Indeterminate Cell Histiocytosis can vary greatly, but often include skin lesions, fever, and fatigue. In some cases, the disease can affect internal organs such as the liver, spleen, and lymph nodes.
Diagnosis
Diagnosis of Indeterminate Cell Histiocytosis is often challenging due to its rarity and the indeterminate nature of the cells involved. It typically involves a biopsy of the affected tissue, followed by microscopic examination and immunohistochemical staining.
Treatment
Treatment for Indeterminate Cell Histiocytosis is largely dependent on the severity and extent of the disease. It may include chemotherapy, radiotherapy, or surgical removal of the affected tissue. In some cases, immunotherapy may also be used.
Related Terms
- Histiocytosis
- Langerhans cell histiocytosis
- Non-Langerhans cell histiocytosis
- Histiocyte
- Immune system
- Biopsy
- Chemotherapy
- Radiotherapy
- Immunotherapy
External links
- Medical encyclopedia article on Indeterminate cell histiocytosis
- Wikipedia's article - Indeterminate cell histiocytosis
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