Hypoxia-inducible factor
| Hypoxia-inducible factor | |
|---|---|
| Term | Hypoxia-inducible factor |
| Short definition | hypoxia-inducible factor - (hy-POK-see-uh-in-DOO-sih-bul FAK-ter) One of a group of proteins that play an important role in how cells respond to changing oxygen levels. When oxygen levels in cells are low, hypoxia-inducible factors activate specific genes involved in cell growth and survival. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
hypoxia-inducible factor - (hy-POK-see-uh-in-DOO-sih-bul FAK-ter) One of a group of proteins that play an important role in how cells respond to changing oxygen levels. When oxygen levels in cells are low, hypoxia-inducible factors activate specific genes involved in cell growth and survival. This allows the cells to function and survive even under oxygen-poor conditions. Hypoxia-inducible factors can be produced in higher than normal amounts by some types of cancer cells. This can cause cancer cells to grow and spread to other parts of the body. Also called HIF
External links
- Medical encyclopedia article on Hypoxia-inducible factor
- Wikipedia's article - Hypoxia-inducible factor
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