Glia limitans
Glia limitans
Glia limitans (pronunciation: /ˈɡliːə lɪˈmɪtæns/) is a thin barrier of astrocytic end-feet and basement membrane that separates the central nervous system (CNS) parenchyma from the meninges.
Etymology
The term "Glia limitans" is derived from the Latin words "glia" meaning "glue" and "limitans" meaning "limiting". It was first used in the late 19th century to describe the limiting layer of glial cells in the CNS.
Function
The Glia limitans serves as a protective barrier, preventing the entry of harmful substances into the CNS. It also plays a crucial role in maintaining the homeostasis of the CNS by regulating the exchange of molecules and cells between the CNS and the peripheral immune system.
Structure
The Glia limitans is composed of two layers: the superficial glia limitans, which is located at the surface of the brain and spinal cord, and the perivascular glia limitans, which surrounds the blood vessels within the CNS. Both layers are made up of astrocytic end-feet that are covered by a basement membrane.
Related Terms
- Astrocyte: A type of glial cell that forms the end-feet that make up the Glia limitans.
- Basement membrane: A thin, fibrous membrane that covers the astrocytic end-feet in the Glia limitans.
- Central nervous system: The part of the nervous system that includes the brain and spinal cord, and is protected by the Glia limitans.
- Meninges: The three layers of protective tissue that cover the CNS and are separated from it by the Glia limitans.
External links
- Medical encyclopedia article on Glia limitans
- Wikipedia's article - Glia limitans
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