Fibrosing colonopathy

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Fibrosing Colonopathy

Fibrosing colonopathy (pronunciation: fi-bro-sing ko-lo-no-pa-thy) is a rare but serious condition that affects the large intestine or colon.

Etymology

The term "fibrosing colonopathy" is derived from three Greek words: "fibrosis" meaning the formation of excess fibrous connective tissue, "colon" referring to the large intestine, and "pathy" meaning disease.

Definition

Fibrosing colonopathy is a condition characterized by thickening or scarring (fibrosis) of the colon. This condition is often associated with the long-term use of high-dose pancreatic enzyme replacement therapy (PERT) in patients with cystic fibrosis.

Symptoms

Symptoms of fibrosing colonopathy may include abdominal pain, bloating, constipation, and weight loss. In severe cases, it can lead to bowel obstruction.

Diagnosis

Diagnosis of fibrosing colonopathy is typically made through a combination of clinical history, physical examination, and imaging studies such as computed tomography (CT) scan or magnetic resonance imaging (MRI). A definitive diagnosis can be made through a biopsy of the colon.

Treatment

Treatment of fibrosing colonopathy involves managing the symptoms and may include changes in the dose or type of PERT, pain management, and nutritional support. In severe cases, surgery may be required.

Related Terms

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