Feulgen stain
Feulgen Stain
Feulgen Stain (pronunciation: /ˈfɔɪɡən/), is a histological staining technique used primarily in the field of cytology. The stain was named after its developer, Robert Feulgen, a German chemist and doctor.
Etymology
The term "Feulgen Stain" is derived from the name of its inventor, Robert Feulgen. Feulgen discovered this staining technique in the early 20th century, while he was working on his research in the field of histology.
Description
Feulgen Stain is a specific nuclear stain used for the demonstration of DNA in cellular specimens. It is based on the reaction of the aldehyde groups, which are produced by partial acid hydrolysis of DNA, with the reagent Schiff's reagent. The result is a magenta coloration of the DNA.
Application
Feulgen Stain is widely used in the field of cytology, histology, and pathology. It is particularly useful in the detection of DNA in various cell types, and is often used in research to quantify DNA, study cell cycle, and detect apoptotic cells.
Related Terms
- Schiff's reagent: A chemical reagent used in Feulgen Stain for the detection of aldehyde groups in DNA.
- DNA: Deoxyribonucleic acid, a molecule that carries most of the genetic instructions used in the development, functioning, and reproduction of all known living organisms and many viruses.
- Cytology: The study of cells.
- Histology: The study of the microscopic structure of tissues.
- Pathology: The study of the causes and effects of disease or injury.
External links
- Medical encyclopedia article on Feulgen stain
- Wikipedia's article - Feulgen stain
This MedicineGPT article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski