Chromosomal fragile site
Chromosomal Fragile Site
Chromosomal fragile site (pronunciation: kroh-MO-soh-muhl FRAY-juhl site) is a specific area on a chromosome that demonstrates an increased susceptibility to forming chromosomal aberrations under certain conditions.
Etymology
The term "chromosomal fragile site" is derived from the Greek word "chroma" meaning color, "soma" meaning body, and the English word "fragile" indicating the susceptibility of these sites to breakage.
Definition
Chromosomal fragile sites are specific loci that preferentially exhibit gaps and breaks on metaphase chromosomes following certain types of cell culture. They are classified into two main types: common fragile sites and rare fragile sites. Common fragile sites are found in all individuals, while rare fragile sites are seen in a few individuals and are often associated with genetic disorders.
Related Terms
- Chromosome: A thread-like structure of nucleic acids and protein found in the nucleus of most living cells, carrying genetic information in the form of genes.
- Chromosomal aberrations: Changes that occur in the structure or number of chromosomes in an organism.
- Common fragile sites: These are specific areas on chromosomes that are prone to breakage and are found in all individuals.
- Rare fragile sites: These are specific areas on chromosomes that are prone to breakage and are found in a few individuals. They are often associated with genetic disorders.
- Genetic disorders: Medical conditions caused by changes in the genetic material within cells.
External links
- Medical encyclopedia article on Chromosomal fragile site
- Wikipedia's article - Chromosomal fragile site
This MedicineGPT article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski