CYP27A1
CYP27A1
CYP27A1 (pronounced as "S-I-P-27-A-1") is a gene that provides instructions for making an enzyme called sterol 27-hydroxylase. This enzyme is involved in the initial steps of bile acid production, which is a complex process that takes place in the liver. Bile acids are used to digest fats and absorb fat-soluble vitamins.
Etymology
The term CYP27A1 is derived from the Cytochrome P450 family of enzymes, with '27A1' indicating its specific subtype. The Cytochrome P450 enzymes are named for their ability to absorb light at a wavelength of 450 nanometers when bound to carbon monoxide.
Function
The CYP27A1 enzyme is involved in the breakdown of cholesterol in the body. It catalyzes the first step of the acidic pathway to bile acids, converting cholesterol to 27-hydroxycholesterol. This process is crucial for the body's cholesterol homeostasis.
Related Terms
- Cholesterol: A type of fat found in your blood. Your liver makes cholesterol for your body. You also can get cholesterol from the foods you eat.
- Enzyme: A substance produced by a living organism which acts as a catalyst to bring about a specific biochemical reaction.
- Gene: The basic physical and functional unit of heredity. Genes are made up of DNA.
- Liver: A large, meaty organ that sits on the right side of the belly. The liver's main job is to filter the blood coming from the digestive tract, before passing it to the rest of the body.
- Bile acids: A group of molecules that are produced in the liver and help with the digestion of dietary fats.
External links
- Medical encyclopedia article on CYP27A1
- Wikipedia's article - CYP27A1
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