Becaplermin
Becaplermin
Becaplermin (pronounced as be-KAP-ler-min) is a recombinant human platelet-derived growth factor used for the treatment of diabetic ulcers that fail to heal on their own. It is marketed under the brand name Regranex.
Etymology
The term "Becaplermin" is derived from the words "beca", which is a prefix used in pharmacology to denote synthetic drugs, and "plermin", which is a suffix used to denote growth factors.
Usage
Becaplermin is used topically to promote the healing of diabetic ulcers. It works by stimulating the growth of cells and tissues, thereby speeding up the healing process. It is usually used in conjunction with good wound care practices such as keeping the wound clean and properly dressed.
Related Terms
- Diabetic Ulcers: These are wounds that are slow to heal or do not heal fully on their own in people with diabetes. They most commonly occur on the feet.
- Platelet-Derived Growth Factor (PDGF): This is a protein that regulates cell growth and division. In particular, it plays a significant role in blood vessel formation.
- Recombinant DNA Technology: This is a technology that allows DNA molecules from different sources to be combined, creating sequences that would not otherwise be found in the genome.
Side Effects
Like all medicines, Becaplermin can cause side effects, although not everybody gets them. Some common side effects include redness, rash, or itching at the site of application. If these persist or worsen, patients are advised to contact their healthcare provider.
Precautions
Becaplermin should not be used in patients with known hypersensitivity to becaplermin or any of the excipients. It should also not be used in patients with malignancies at the site of application.
External links
- Medical encyclopedia article on Becaplermin
- Wikipedia's article - Becaplermin
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