BRAF (V600E) kinase inhibitor RO5185426

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BRAF (V600E) kinase inhibitor RO5185426
TermBRAF (V600E) kinase inhibitor RO5185426
Short definitionBRAF (V600E) kinase inhibitor RO5185426 - drug used to treat Erdheim-Chester disease (a very rare form of histiocytosis) and advanced melanoma, which have a specific mutation (change) in melanomaBRAFGen. It is also being studied in the treatment of other types of cancer. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


BRAF (V600E) kinase inhibitor RO5185426 - drug used to treat Erdheim-Chester disease (a very rare form of histiocytosis) and advanced melanoma, which have a specific mutation (change) in melanomaBRAFGen. It is also being studied in the treatment of other types of cancer. BRAF (V600E) kinase inhibitor RO5185426 blocks certain proteins produced by the mutationBRAFGene that can help stop cancer cells from growing. It's a kind of kinase inhibitor. Also called PLX4032, RG7204, vemurafenib and Zelboraf

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