BCR-ABL fusion gene
| BCR-ABL fusion gene | |
|---|---|
| Term | BCR-ABL fusion gene |
| Short definition | BCR-ABL fusion gene - gene that results when parts of chromosomes 9 and 22 break off and swap places. The ABL gene on chromosome 9 joins with the BCR gene on chromosome 22 to form the BCR-ABL fusion gene. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
BCR-ABL fusion gene - gene that results when parts of chromosomes 9 and 22 break off and swap places. The ABL gene on chromosome 9 joins with the BCR gene on chromosome 22 to form the BCR-ABL fusion gene. The altered chromosome 22 with the fusion gene on it is called the Philadelphia chromosome. The BCR-ABL fusion gene is found in most patients with chronic myeloid leukemia (CML) and in some patients with acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML)
External links
- Medical encyclopedia article on BCR-ABL fusion gene
- Wikipedia's article - BCR-ABL fusion gene
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