Axicabtagen-Ciloleucel
| Axicabtagen-Ciloleucel | |
|---|---|
| Term | Axicabtagen-Ciloleucel |
| Short definition | Axicabtagen-Ciloleucel (AK-see-KAB-tuh-jeen sy-loh-LOO-sel) drug used to treat adults with follicular lymphoma or certain types of large B-cell lymphoma that has relapsed (returned) or failed to improve after treatment with at least two other systemic therapies. It is also being studied in the treatment of other types of cancer. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
Axicabtagen-Ciloleucel - (pronounced) (AK-see-KAB-tuh-jeen sy-loh-LOO-sel) drug used to treat adults with follicular lymphoma or certain types of large B-cell lymphoma that has relapsed (returned) or failed to improve after treatment with at least two other systemic therapies. It is also being studied in the treatment of other types of cancer. Axicabtagene ciloleucel is made using a patient's T cells (a type of cell in the immune system). A gene for a special receptor called the chimeric antigen receptor (CAR) is added to the T cells in the laboratory. Large numbers of these modified T cells, known as CAR T cells, are cultivated in the laboratory and given to the patient by infusion. Axicabtagene ciloleucel attaches to a protein called CD19, which is found on most B-cell lymphoma cells. This helps the body's immune system kill cancer cells. Axicabtagene-Ciloleucel is a form of CAR-T cell therapy. Also called Yescarta
External links
- Medical encyclopedia article on Axicabtagen-Ciloleucel
- Wikipedia's article - Axicabtagen-Ciloleucel
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