Arias-Stella reaction
Arias-Stella reaction
The Arias-Stella reaction (pronunciation: /ˈɑːrɪəs ˈstɛlə rɪˈækʃən/) is a histopathological finding in the endometrium that is often associated with pregnancy, but can also occur in non-pregnant conditions.
Etymology
The term is named after the Peruvian pathologist, Javier Arias-Stella, who first described the condition in 1954.
Definition
The Arias-Stella reaction is characterized by the presence of enlarged, atypical endometrial gland cells with clear or eosinophilic cytoplasm and prominent nucleoli. These changes are typically seen in the endometrium during early pregnancy, but can also occur in response to exogenous progesterone therapy or in ectopic pregnancy.
Related Terms
- Endometrium: The inner lining of the uterus, which undergoes cyclic changes during the menstrual cycle and plays a crucial role in pregnancy.
- Progesterone: A hormone produced by the ovaries that prepares the lining of the uterus for implantation of a fertilized egg and helps maintain pregnancy.
- Ectopic pregnancy: A pregnancy that occurs outside the uterus, most commonly in the fallopian tubes.
See Also
- Decidual reaction: A change in the endometrium in response to progesterone, characterized by the transformation of stromal fibroblasts into large, polygonal decidual cells.
- Endometrial hyperplasia: A condition characterized by the thickening of the endometrium, often due to excessive estrogen without progesterone.
External links
- Medical encyclopedia article on Arias-Stella reaction
- Wikipedia's article - Arias-Stella reaction
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