Allylamines
Allylamines
Allylamines (pronunciation: al-lyl-a-mines) are a class of antifungal drugs that inhibit the enzyme squalene epoxidase, which is necessary for the synthesis of ergosterol, an important component of fungal cell membranes.
Etymology
The term "Allylamines" is derived from the chemical structure of these compounds, which contain an allyl group (a carbon atom double-bonded to two other carbon atoms) and an amine group (a nitrogen atom bonded to one or more hydrogen atoms).
Related Terms
- Antifungal: A substance that inhibits or kills fungi.
- Squalene epoxidase: An enzyme involved in the biosynthesis of sterols, including ergosterol.
- Ergosterol: A sterol found in cell membranes of fungi and protozoa, serving many of the same functions that cholesterol serves in animal cells.
Usage
Allylamines are used to treat a variety of fungal infections, including tinea pedis (athlete's foot), tinea cruris (jock itch), and tinea corporis (ringworm). They are available in both topical and oral formulations. Examples of allylamines include terbinafine and naftifine.
Side Effects
Like all medications, allylamines can cause side effects. These may include skin irritation, burning, or itching at the application site for topical formulations, and gastrointestinal symptoms, headache, or changes in taste for oral formulations.
Precautions
Before using allylamines, individuals should inform their healthcare provider about any other medications they are taking, as well as any allergies or other health conditions they have.
External links
- Medical encyclopedia article on Allylamines
- Wikipedia's article - Allylamines
This MedicineGPT article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski