National Centre for the Replacement, Refinement and Reduction of Animals in Research

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National Centre for the Replacement, Refinement and Reduction of Animals in Research (pronunciation: /ˈnæʃənəl ˈsɛntər fɔr ðə rɪˈpleɪsmənt, rɪˈfaɪnmənt ænd rɪˈdʌkʃən ɒv ˈænɪməlz ɪn rɪˈsɜːrtʃ/), often abbreviated as NC3Rs, is a UK-based scientific organization dedicated to promoting and advancing the 3Rs (Replacement, Refinement, Reduction) in animal research.

Etymology

The name of the organization is derived from the three Rs principle, which stands for Replacement, Refinement, and Reduction. This principle was first proposed by William M. S. Russell and Rex L. Burch in their 1959 book "The Principles of Humane Experimental Technique".

Related Terms

  • 3Rs: An acronym for Replacement, Refinement, and Reduction, the three guiding principles for more ethical use of animals in testing and research.
  • Animal testing: The use of non-human animals in experiments and development of products, often for the purpose of determining the safety of substances such as foods or drugs.
  • Ethics in animal research: The moral considerations and guidelines that govern the use of animals in scientific research.
  • In vitro: A term used in biology to refer to experiments conducted in a controlled environment outside of a living organism, often used as an alternative to animal testing.
  • In vivo: A term used in biology to refer to experiments conducted within a living organism, often involving the use of animals in research.

See Also

References


External links

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