MUC5AC
MUC5AC (pronounced as "muck-five-a-c") is a type of Mucin, specifically a gel-forming mucin, that is secreted by the goblet cells of the respiratory and digestive tracts. The term "MUC5AC" is derived from the abbreviation for "Mucin 5AC, oligomeric mucus/gel-forming".
Etymology
The term "MUC5AC" is an abbreviation where "MUC" stands for Mucin, "5" represents the subtype, and "AC" is a specific identifier for this type of mucin. Mucins are a family of high molecular weight, heavily glycosylated proteins produced by epithelial tissues in most animals.
Function
MUC5AC plays a crucial role in the protection and lubrication of many body linings, including the respiratory, gastrointestinal, and reproductive tracts. It also plays a role in cell signaling, which can influence cell growth and differentiation.
Clinical Significance
Alterations in MUC5AC expression or function have been associated with many respiratory diseases, including Chronic Obstructive Pulmonary Disease (COPD), Asthma, and Cystic Fibrosis. In the digestive tract, changes in MUC5AC may be associated with peptic ulcers and Gastric Cancer.
Related Terms
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