Cyclic AMP
Cyclic AMP
Cyclic AMP (pronounced as /ˈsaɪklɪk æmp/), also known as cAMP or cyclic adenosine monophosphate, is a crucial biochemical messenger in both prokaryotes and eukaryotes. It is derived from adenosine triphosphate (ATP) and used for intracellular signal transduction.
Etymology
The term "Cyclic AMP" is derived from its structure. The molecule is a cyclic form of adenosine monophosphate (AMP), hence the name "Cyclic AMP". The prefix "cyclic" refers to the circular structure of the molecule, while "AMP" is an acronym for adenosine monophosphate.
Function
Cyclic AMP functions as a secondary messenger in many biological processes. It is involved in the regulation of glycogen, sugar, and lipid metabolism. In response to hormonal stimulation, cyclic AMP activates protein kinase A (PKA), leading to a series of phosphorylation reactions that result in physiological responses.
Synthesis and Degradation
Cyclic AMP is synthesized from ATP by the enzyme adenylyl cyclase, which is located at the cell membrane. The degradation of cyclic AMP into AMP is catalyzed by the enzyme phosphodiesterase.
Related Terms
- Adenosine triphosphate (ATP)
- Adenylyl cyclase
- Protein kinase A (PKA)
- Phosphodiesterase
- Glycogen
- Sugar
- Lipid
External links
- Medical encyclopedia article on Cyclic AMP
- Wikipedia's article - Cyclic AMP
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