Lasmiditan

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Lasmiditan

Lasmiditan (pronounced la-smi-di-tan) is a ditan molecule developed for the acute treatment of migraine. It is a selective serotonin receptor agonist.

Etymology

The term "Lasmiditan" is derived from the class of drugs it belongs to, known as "ditans". The prefix "Las" is a unique identifier for this specific molecule within the ditan class.

Pharmacology

Lasmiditan is a highly selective agonist for the 5-HT1F receptor, a subtype of the serotonin receptor. It does not constrict blood vessels, which distinguishes it from other migraine medications like triptans.

Clinical Use

Lasmiditan is used for the acute treatment of migraine with or without aura in adults. It is not indicated for the preventive treatment of migraine.

Side Effects

Common side effects of Lasmiditan include dizziness, fatigue, paresthesia, and sedation. It is contraindicated in patients with severe hepatic impairment.

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