Integrin

Integrin
Term	Integrin
Short definition	Integrin (IN-teh-grin) A type of protein found on the surface of cells that helps them attach to and communicate with neighboring cells. Integrins also help cells attach to large molecules in the extracellular matrix, the substance that surrounds cells and gives them structure.
Type	Cancer terms
Specialty	Oncology
Language	English
Source	NCI
Comments

Integrin - (pronounced) (IN-teh-grin) A type of protein found on the surface of cells that helps them attach to and communicate with neighboring cells. Integrins also help cells attach to large molecules in the extracellular matrix, the substance that surrounds cells and gives them structure. Integrins help cells receive signals from other cells and the environment, and they help control the activity of certain genes. They play an important role in cell growth, cell movement and other cell functions. Integrins are involved in wound healing, blood vessel growth, and the growth and spread of cancer cells. Drugs that target integrins are being studied to treat some types of cancer

External links

• Medical encyclopedia article on Integrin
• Wikipedia's article - Integrin

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