View source for PRO 140

== PRO 140 ==

'''PRO 140''' (pronounced P-R-O One-Four-Zero) is a [[monoclonal antibody]] designed to treat [[HIV]] and [[HIV/AIDS|AIDS]]. It is a [[biological therapy]] that works by blocking the [[CCR5]] receptor, which the HIV virus uses to enter and infect [[T cells]].

=== Etymology ===

The name "PRO 140" is derived from its development by the biotechnology company [[Progenics Pharmaceuticals]]. The "140" does not have a known specific meaning.

=== Mechanism of Action ===

PRO 140 works by binding to the CCR5 receptor on the surface of T cells. This prevents the HIV virus from attaching to the cell and entering it, thereby preventing the virus from replicating and spreading throughout the body.

=== Related Terms ===

* [[Monoclonal antibody]]: A type of protein made in the lab that can bind to substances in the body, including cancer cells.
* [[CCR5]]: A protein on the surface of white blood cells that is involved in the immune system as it functions as a receptor for chemokines.
* [[HIV]]: Human Immunodeficiency Virus, the virus that causes AIDS.
* [[AIDS]]: Acquired Immunodeficiency Syndrome, a chronic, potentially life-threatening condition caused by the human immunodeficiency virus (HIV).
* [[T cells]]: A type of white blood cell that is of key importance to the immune system and is at the core of adaptive immunity, the system that tailors the body's immune response to specific pathogens.

[[Category:Medicine]]
[[Category:Pharmaceuticals]]
[[Category:HIV/AIDS]]

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