View source for Kappa-opioid receptor

== Kappa-opioid receptor ==

The '''Kappa-opioid receptor''' ('''KOR''') is a type of [[opioid receptor]] which binds to [[kappa-opioids]] such as [[dynorphin]], a natural peptide that is found in the human body. The pronunciation of Kappa-opioid receptor is /ˈkæpə ˈoʊpiɔɪd rɪˈsɛptər/.

=== Etymology ===

The term "Kappa-opioid receptor" is derived from the Greek letter kappa (κ), used to denote this type of opioid receptor, and the term "opioid receptor", which refers to a group of [[G protein-coupled receptors]] with opioids as ligands.

=== Function ===

The Kappa-opioid receptor plays a key role in the regulation of [[pain]], [[mood]], [[consciousness]], [[motor control]], and [[immune response]]. Activation of the KOR can lead to analgesic effects, as well as feelings of [[dysphoria]] and [[hallucinations]].

=== Related Terms ===

* [[Opioid receptor]]: A type of protein found on the surface of cells that binds to opioids.
* [[Dynorphin]]: An endogenous opioid that acts as a ligand for the KOR.
* [[G protein-coupled receptors]]: A large protein family of receptors that sense molecules outside the cell and activate inside signal transduction pathways.
* [[Dysphoria]]: A profound state of unease or dissatisfaction, often associated with depression.
* [[Hallucinations]]: Perceptions in a conscious and awake state in the absence of external stimuli which have qualities of real perception.

[[Category:Neuroscience]]
[[Category:Pharmacology]]
[[Category:Medicine]]

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