View source for Ioflupane (123I)

'''Ioflupane (123I)'''

'''Ioflupane (123I)''' (pronounced eye-oh-floo-pane) is a [[radiopharmaceutical]] compound used in [[nuclear medicine]] for the diagnosis of [[Parkinson's disease]] and [[dementia with Lewy bodies]]. It is a [[radiotracer]] that binds to [[dopamine transporter]] proteins in the brain, allowing for imaging using [[single-photon emission computed tomography]] (SPECT).

==Etymology==

The term "Ioflupane" is derived from the compound's chemical structure, which includes iodine (I), fluoro (Flu), and propane. The "(123I)" denotes the specific isotope of iodine used, iodine-123.

==Usage==

Ioflupane (123I) is administered intravenously and is used in conjunction with SPECT imaging to visualize the distribution of dopamine transporters in the brain. This can help in the differential diagnosis of Parkinson's disease and other parkinsonian syndromes.

==Related Terms==

* [[Radiopharmaceutical]]: A radioactive compound used for diagnostic or therapeutic purposes.
* [[Nuclear medicine]]: A medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease.
* [[Parkinson's disease]]: A long-term degenerative disorder of the nervous system that mainly affects the motor system.
* [[Dementia with Lewy bodies]]: A type of progressive dementia that leads to a decline in thinking, reasoning and independent function.
* [[Radiotracer]]: A radioactive tracer used in medical imaging to help visualize certain tissues or organs.
* [[Dopamine transporter]]: A membrane-spanning protein that pumps the neurotransmitter dopamine out of the synapse back into cytosol.
* [[Single-photon emission computed tomography]] (SPECT): A nuclear medicine tomographic imaging technique using gamma rays.

[[Category:Radiopharmaceuticals]]
[[Category:Nuclear Medicine]]
[[Category:Parkinson's disease]]
[[Category:Dementia with Lewy bodies]]

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