View source for BMS-906024

== BMS-906024 ==

'''BMS-906024''' (/bɪms naɪn oʊ sɪks oʊ tuː fɔːr/) is a potent and selective [[gamma-secretase]] inhibitor that is currently under investigation for its potential therapeutic applications in the treatment of [[cancer]].

=== Etymology ===

The term "BMS-906024" is a proprietary designation given by the pharmaceutical company [[Bristol-Myers Squibb]]. The "BMS" stands for Bristol-Myers Squibb, while the numerical sequence "906024" is an arbitrary designation used for identification purposes.

=== Related Terms ===

* [[Gamma-secretase]]: An intramembrane protease that plays a crucial role in cellular processes such as [[Notch signaling pathway|Notch signaling]] and [[amyloid precursor protein]] processing. Inhibition of gamma-secretase is a potential therapeutic strategy in cancer treatment.
* [[Notch signaling pathway]]: A highly conserved cell signaling system present in most multicellular organisms. Malfunctions in this pathway can lead to various forms of cancer.
* [[Amyloid precursor protein]]: A transmembrane protein that is processed by gamma-secretase. Abnormal processing of this protein is implicated in the development of [[Alzheimer's disease]].
* [[Bristol-Myers Squibb]]: A global biopharmaceutical company that is the developer of BMS-906024.

=== See Also ===

* [[Gamma-secretase inhibitor]]
* [[Notch signaling pathway]]
* [[Amyloid precursor protein]]
* [[Alzheimer's disease]]
* [[Bristol-Myers Squibb]]

[[Category:Pharmaceuticals]]
[[Category:Cancer treatments]]
[[Category:Medical terminology]]
[[Category:Biochemistry]]

{{dictionary-stub}}