View source for 11-Nor-9-carboxy-THC

== 11-Nor-9-carboxy-THC ==

'''11-Nor-9-carboxy-THC''' (pronounced as "eleven-nor-nine-carboxy-T-H-C"), also known as '''THC-COOH''', is a secondary metabolite of [[Tetrahydrocannabinol|THC]], the primary psychoactive compound found in [[Cannabis (drug)|cannabis]]. 

=== Etymology ===

The term "11-Nor-9-carboxy-THC" is derived from the chemical structure of the compound. The "11-Nor" refers to the absence of a carbon atom at the 11th position in the molecule, and the "9-carboxy" refers to the presence of a carboxyl group at the 9th position. The "THC" in the name stands for [[Tetrahydrocannabinol]], the parent compound from which 11-Nor-9-carboxy-THC is metabolized.

=== Metabolism ===

When THC is consumed, it is metabolized in the liver by the enzyme [[Cytochrome P450|cytochrome P450]]. One of the primary metabolites produced is 11-Nor-9-carboxy-THC. This metabolite is not psychoactive, meaning it does not produce the "high" associated with THC. However, it is often detected in urine drug tests as a marker for recent cannabis use.

=== Detection ===

11-Nor-9-carboxy-THC is the primary metabolite detected in urine drug tests for cannabis. It can be detected for a longer period of time after cannabis use than THC itself, making it a more reliable marker for recent use. The detection window can vary depending on the frequency and quantity of cannabis use, as well as individual metabolic factors.

=== Related Terms ===

* [[Tetrahydrocannabinol|THC]]: The primary psychoactive compound in cannabis, from which 11-Nor-9-carboxy-THC is metabolized.
* [[Cannabis (drug)|Cannabis]]: The plant species that produces THC.
* [[Cytochrome P450|Cytochrome P450]]: The enzyme that metabolizes THC into 11-Nor-9-carboxy-THC.
* [[Drug test|Drug test]]: A test that can detect the presence of 11-Nor-9-carboxy-THC in urine.

[[Category:Medical Dictionary]]
[[Category:Cannabis]]
[[Category:Metabolites]]
[[Category:Drug Testing]]

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